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FDA Shortage Check

Is Depo-medrol (Methylprednisolone Acetate Injection) in shortage?

Label: plusbeauxjours · shortage label · not a prescription, not a pharmacy, not FDA

IN SHORTAGE

Depo-medrol: in shortage (FDA, Oct 24)

Injections (vials)
A generic injection, not your medicine. We draw dosage forms, not products, and never pills you could match to yours.
  • Reason: “Demand increase for the drug”. FDA shortage reason (FDASIA), reported by the manufacturer
  • Reason: “Other”. FDA shortage reason (FDASIA), reported by the manufacturer
  • Estimate: “Estimated recovery: late October 2026/November 2026”. Manufacturer’s estimate, Amneal Pharmaceuticals, Oct 6, 2026
DRUG
Depo-medrol
FDA LISTING
FORM
injection
STATUS
Currently in Shortage
FIRST POSTED
Dec 15, 2021
LAST FDA UPDATE
Oct 21, 2026
AS OF
Oct 24, 2026
SOURCE

FDA lists 23 presentations: 4 unavailable · 9 limited · 10 available.

FDA Drug Shortages checked Oct 24, 2026, 21:05 ET · FDA updates daily · manufacturer-reported

Information from FDA’s drug shortage list, reported by manufacturers. Not medical advice. Don’t stop, change or ration a medicine without talking to your prescriber or pharmacist.

FDA's listing, word for word: Methylprednisolone Acetate Injection. 23 presentations from 5 makers.

Check your own medication, form and strength

What to ask at the counter

  1. Is this a supply problem at this pharmacy, or everywhere? Could another pharmacy have it? FDA consumer FAQ (opens in a new tab)
  2. Is my strength or the maker you stock affected? FDA list, by presentation
  3. Is there an alternative to this medicine I should ask my prescriber about? FDA consumer FAQ (opens in a new tab)
  4. When should I check back, or can you order it?

FDA: “talk with your health care provider or pharmacist for other treatment options during the shortage.” FDA Drug Shortages page (opens in a new tab)

This listing on FDA ↗ (opens in a new tab)Report a shortage to FDA: drugshortages@fda.hhs.gov

Every presentation FDA lists, by maker

Availability is FDA's text for each package, as the manufacturer reported it. Makers with unavailable or limited packages come first.

Amneal Pharmaceuticals4 presentations · 1 limited · 3 available or not stated

Contact (FDA's listing): 866-525-7270

  • 40 mg/1 mL

    Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-1)

    Estimated recovery: late October 2026/November 2026

    NDC 70121-1573-1Revised

    Limited Availability

  • 40 mg/1 mL

    Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 70121-1573-5)

    NDC 70121-1573-5Revised

    Available

  • 80 mg/1 mL

    Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-1)

    NDC 70121-1574-1Revised

    Available

  • 80 mg/1 mL

    Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 70121-1574-5)

    NDC 70121-1574-5Revised

    Available

Eugia US LLC2 presentations · 2 unavailable

Contact (FDA's listing): 888-238-7880

  • 40 mg/1 mL

    Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 55150-313-01)

    On backorder. Recovery: TBD. Check wholesalers for inventory

    NDC 55150-313-01Reverified

    Unavailable

  • 80 mg/1 mL

    Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 55150-314-01)

    On backorder. Recovery: TBD. Check wholesalers for inventory

    NDC 55150-314-01Reverified

    Unavailable

Par Health, USA LLC1 presentation · 1 unavailable

Contact (FDA's listing): 800-828-9393

  • 80 mg/1 mL

    Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 42023-240-01)

    Estimated recovery: TBD

    NDC 42023-240-01Reverified

    Unavailable

Pfizer Inc.13 presentations · 1 unavailable · 6 limited · 6 available or not stated

Contact (FDA's listing): 844-646-4398

  • 40 mg/1 mL

    Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-02)

    Next Delivery: November 2026; Estimated Recovery: December 2026

    NDC 0009-0280-02Revised

    Unavailable

  • 40 mg/1 mL

    Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-03)

    Limited Supply Available. Next Delivery: November 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay

    NDC 0009-0280-03Revised

    Limited Availability

  • 40 mg/1 mL

    Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-51)

    Limited Supply Available. Next Delivery: November 2026; Estimated Recovery: December 2026

    NDC 0009-0280-51Revised

    Limited Availability

  • 40 mg/1 mL

    Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-01)

    Limited Supply Available. Next Delivery: October 2026; Estimated Recovery: December 2026

    NDC 0009-3073-01Revised

    Limited Availability

  • 40 mg/1 mL

    Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-03)

    Limited Supply Available. Next Delivery: November 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay

    NDC 0009-3073-03Revised

    Limited Availability

  • 80 mg/1 mL

    Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-01)

    Limited Supply Available. Next Delivery and Estimated Recovery: December 2026

    NDC 0009-3475-01Revised

    Limited Availability

  • 80 mg/1 mL

    Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-3475-03)

    Limited Supply Available. Next Delivery: October 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay

    NDC 0009-3475-03Revised

    Limited Availability

  • 20 mg/1 mL

    Depo-medrol, Injection, 20 mg/1 mL (NDC 0009-0274-01)

    NDC 0009-0274-01Reverified

    Available

  • 40 mg/1 mL

    Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-0280-52)

    NDC 0009-0280-52Reverified

    Available

  • 40 mg/1 mL

    Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-22)

    NDC 0009-3073-22Revised

    Available

  • 40 mg/1 mL

    Depo-medrol, Injection, 40 mg/1 mL (NDC 0009-3073-23)

    NDC 0009-3073-23Revised

    Available

  • 80 mg/1 mL

    Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-02)

    NDC 0009-0306-02Reverified

    Available

  • 80 mg/1 mL

    Depo-medrol, Injection, 80 mg/1 mL (NDC 0009-0306-12)

    NDC 0009-0306-12Reverified

    Available

Sagent Pharmaceuticals3 presentations · 2 limited · 1 available or not stated

Contact (FDA's listing): 866-625-1618

  • 40 mg/1 mL

    Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-10)

    Limited product available. Estimated recovery: October 2026

    NDC 25021-820-10Revised

    Limited Availability

  • 80 mg/1 mL

    Methylprednisolone Acetate, Injection, 80 mg/1 mL (NDC 25021-821-05)

    Estimated recovery: November 2026, Product on hand is 8-12 months of dating prior to expiry

    NDC 25021-821-05Reverified

    Limited Availability

  • 40 mg/1 mL

    Methylprednisolone Acetate, Injection, 40 mg/1 mL (NDC 25021-820-05)

    NDC 25021-820-05Revised

    Available

What the manufacturers told FDA

  • Amneal Pharmaceuticals · ‘Estimated recovery: late October 2026/November 2026’ · updated Oct 2026
  • Eugia US LLC · ‘On backorder. Recovery: TBD. Check wholesalers for inventory’ · updated Oct 2026
  • Par Health, USA LLC · ‘Estimated recovery: TBD’ · updated Oct 2026
  • Pfizer Inc. · ‘Limited Supply Available. Next Delivery and Estimated Recovery: December 2026’ · updated Oct 2026
  • Pfizer Inc. · ‘Limited Supply Available. Next Delivery: November 2026; Estimated Recovery: December 2026’ · updated Oct 2026

More on FDA ↗ (opens in a new tab)

Reason for the shortage (FDASIA)

  • Demand increase for the drug
  • Other
  • Shortage of an active ingredient

As reported by the manufacturer under the Food and Drug Administration Safety and Innovation Act.

Alternatives

FDA lists none: “Providing a list of alternative drug products for a drug in shortage is part of the ‘practice of medicine.’ FDA does not regulate the practice of medicine.” Your prescriber or pharmacist can talk through options with you. ASHP also tracks shortages and suggested alternatives (different criteria) ↗ (opens in a new tab)

Questions

Is Depo-medrol in shortage?
Yes. As of Oct 24, 2026, FDA lists Methylprednisolone Acetate Injection as currently in shortage: 23 presentations, 4 unavailable and 9 limited.
When will the Depo-medrol shortage end?
FDA gives no end date. 11 presentations carry a manufacturer’s own estimate, quoted on this page with its date.
Does FDA list alternatives to Depo-medrol?
No. FDA calls a list of alternatives part of the ‘practice of medicine’. Ask your pharmacist or prescriber.