Is Lorbrena being discontinued?

As of Oct 24, 2026, FDA lists discontinuation notices for Lorlatinib Tablet, not a shortage. A discontinuation “does not necessarily create a shortage” (FDA).

When will the Lorbrena shortage end?

FDA gives no end date, and no manufacturer posted a recovery estimate for this listing.

Does FDA list alternatives to Lorbrena?

No. FDA calls a list of alternatives part of the ‘practice of medicine’. Ask your pharmacist or prescriber.

Is Lorbrena (Lorlatinib Tablet) being discontinued?

Label: plusbeauxjours · shortage label · not a prescription, not a pharmacy, not FDA

DISCONTINUATION NOTICE

Lorbrena: being discontinued (FDA, Oct 24)

Tablets

A generic tablet, not your medicine. We draw dosage forms, not products, and never pills you could match to yours.

DRUG

Lorbrena

FDA LISTING

Lorlatinib Tablet

FORM

tablets

STATUS

Discontinuation

FIRST POSTED

Jun 15, 2026

LAST FDA UPDATE

Jun 15, 2026

AS OF

Oct 24, 2026

SOURCE

FDA Drug Shortages ↗ (opens in a new tab)

1 discontinuation notice below, in FDA's words. A discontinuation “does not necessarily create a shortage” (FDA).

FDA Drug Shortages checked Oct 24, 2026, 21:05 ET · FDA updates daily · manufacturer-reported

Information from FDA’s drug shortage list, reported by manufacturers. Not medical advice. Don’t stop, change or ration a medicine without talking to your prescriber or pharmacist.

FDA's listing, word for word: Lorlatinib Tablet. 1 presentation from 1 maker.

Check your own medication, form and strength

What to ask at the counter

Is this a supply problem at this pharmacy, or everywhere? Could another pharmacy have it? FDA consumer FAQ (opens in a new tab)
Is my strength or the maker you stock affected? FDA list, by presentation
Is there an alternative to this medicine I should ask my prescriber about? FDA consumer FAQ (opens in a new tab)
When should I check back, or can you order it?

FDA: “talk with your health care provider or pharmacist for other treatment options during the shortage.” FDA Drug Shortages page (opens in a new tab)

This listing on FDA ↗ (opens in a new tab)Report a shortage to FDA: drugshortages@fda.hhs.gov

Discontinuation notices

A discontinuation “does not necessarily create a shortage” (FDA).

Pfizer Inc. told FDA it will discontinue Lorbrena (posted Jun 15, 2026).
“Supply expected to exhaust 6/30/2026; NDC 0069-0227-01 25 mg; 30 tablets bottle with a child-resistant closure will continue to be manufactured; Discontinuation of the manufacture of this presentation”
FDA listing: Lorlatinib Tablet

Alternatives

FDA lists none: “Providing a list of alternative drug products for a drug in shortage is part of the ‘practice of medicine.’ FDA does not regulate the practice of medicine.” Your prescriber or pharmacist can talk through options with you. ASHP also tracks shortages and suggested alternatives (different criteria) ↗ (opens in a new tab)

Questions

Is Lorbrena being discontinued?: As of Oct 24, 2026, FDA lists discontinuation notices for Lorlatinib Tablet, not a shortage. A discontinuation “does not necessarily create a shortage” (FDA).
When will the Lorbrena shortage end?: FDA gives no end date, and no manufacturer posted a recovery estimate for this listing.
Does FDA list alternatives to Lorbrena?: No. FDA calls a list of alternatives part of the ‘practice of medicine’. Ask your pharmacist or prescriber.